I am pleased to present my group members and our research on the following pages. Our research is focused on the mechanisms responsible for regulation of cytokine signaling in prostate cancer and androgen receptor coactivators. We have analyzed the role of suppressors of cytokine signaling-3 and -1 in prostate cancer cell proliferation, apoptosis, and migration. We are proud of recent contributions of Martin who recieved national and international awards. It is hoped that understanding of action of suppressors of cytokine signaling (SOCS) in prostate cancer will lead to a more rational and personalized therapy for carcinoma of the prostate. Society for Basic Urological Research has designed my lecture on SOCS American Urological Association (AUA) lecture during the Annual Meeting in Atlanta. Frédéric has continued investigations on cofactors p300 and CBP, which are overexpressed in human prostate cancer. Frédéric and Martin provide expert day-to-day supervision to our students Su, Holger, and Julia who are in early stages of their career. After many years of contribution which resulted with highly recognized publications and awards Ilaria continues her scientific career as an independent researcher in Milan. We greatly appreciate Ilaria´s contributions and interaction with other lab members. We gladly continue our collaborations with several other European research groups in the EU training program „PRO-NEST.“